Which WR will it cost you, Shawn? As defending champs, each team is bringing it hard to the Saints this year....that D will be pressured a lot. Not sure I rank them as highly as some people have them.
I never put a lot of stock in D and K. Always my last two picks of the draft, and usually go week to week with both...all depending on matchup. I picked up Arizona for week 1 vs Sammy Bradford and the Rams too.
One of the leagues i'm in has 3
STARTING QB for EACH week, and the stats are heavily weighted towards QB's with bonuses that are very easily attained. 10 teams...that's 30 starting QB/week. The NFL only starts 31! 8th pick in the draft, and needless to say I went QB with 5 of my first 6 picks
Aaron Rodgers
Matt Schaub
Kevin Kolb
Matt Ryan
Alex Smith
I grabbed Dennis Dixon off waivers too. Thinking about starting Rodgers, Schaub, and Ryan week 1. My opponent has Derek Anderson, Charlie Batch, and Vick!

A lot of people drafted like morons, so now I have people making ridiculously absurd offers for my QB's. Colston for Schaub straight up? HA!
Rest of the lineup: Crabtree, Dez Bryant, Mike Wallace, LeSean McCoy, Zach Miller, Bush, Moreno, Forsett, F. Jones, Hightower, Hoosh. Doesn't really matter too much who I throw in each week, as long as my QB's put up decent numbers this one should easy.